Does Lion’s Mane cause hair loss?

Ismail Yusibov
Ismail Yusibov is the founder and content writer of the AlopeciaTips.

 Fact checked by Jessica Anderson

Written by Ismail Yusibov | Reviewed by Dr. Michael Carter

Lion’s Mane is a medicinal mushroom that was once used in the East for a variety of ancient treatments. In the last 10 years, it has been understood that Lion’s Mane is a powerful DHT blocker and the question of whether it can be an alternative in the treatment of hair loss has been raised. Some people also wonder if Lion’s Mane can cause hair loss.


Lion’s Mane doesn’t treat hair loss. It contains proteins called Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF), which some studies suggest may be linked to hair loss.

Could Lion’s Mane be an alternative to hair loss treatments?

Lion’s Mane doesn’t treat hair loss, but it contains Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF). These substances help nerve regeneration and support the brain. They can produce a mixture of many proteins called Cerebrolysin, which is good for memory and brain health. However, it’s important to note that some studies have suggested that high levels of BDNF might contribute to hair loss. So, while Lion’s Mane is good for your brain, it could potentially affect your hair.

What is Lion’s Mane?

Cerebrolysin is a protein mixture purified from the pig brain. It’s not just one protein, but a combination of many. When you consume Lion’s Mane, it can boost the effects of Cerebrolysin. Cerebrolysin is used in treatments for memory, cognitive health, and stroke.

Lion’s Mane has been shown to lower high levels of the DHT hormone, a major cause of male pattern baldness. Similar to medications like Finasteride, Lion’s Mane is supposed to help prevent your hair from falling out and promote hair growth.

Research shows that Lion’s Mane may reduce DHT-related hair loss by blocking the enzyme 5-alpha reductase, which converts testosterone to DHT. Additionally, Lion’s Mane may improve hair health by increasing blood circulation, offering antioxidant benefits, and increasing nerve growth factor (NGF) production.

Although it is known for being a powerful DHT blocker, Lion’s Mane actually prevents hair loss only in theory.

However, Lion’s Mane could potentially lead to hair loss because it contains a protein called Brain-Derived Neurotrophic Factor (BDNF). BDNF influences human hair growth through tropomyosin receptors (TrkB) and can slow down hair growth, trigger early hair shedding, and reduce the production of keratinocytes.

We break the myth: should you use Lion’s Mane to treat hair loss?

Never use Lion’s Mane to treat hair loss. Using Lion’s Mane to stop hair loss and promote hair growth will cause hair loss after a while.

Many sources I browsed on the internet say that Lion’s Mane can treat hair loss because it has a strong DHT-blocking feature. But this is not true. In fact, Lion’s Mane is a powerful DHT blocker, but this is not enough for its ability to treat hair loss.

It has been scientifically proven that Lion’s Mane can cause hair loss due to the proteins it contains. If you are looking for a proven method for hair loss treatment, you can turn to drugs such as Finasteride or Minoxidil with the supervision of a doctor.

So, what is Lion’s Mane used for?

Lion’s Mane has a wide range of uses in medicine. This mushroom is used in many treatments because it supports brain health. Especially its effect on improving memory is the strongest feature of Lion’s Mane. Today, Lion’s Mane is being tested as a treatment for Alzheimer’s.

Inflammation and oxidation properties

Lion’s Mane fights inflammation, which causes inflammation and oxidation in the body. Inflammation can cause many problems, including diabetes, heart disease and autoimmune diseases.

Strengthens the immune system

Lion’s Mane mushrooms reduce inflammation in the body and strengthen the immune system. Many experiments on animals have proven the immune-boosting effect of Lion’s Mane.

Improves depression, anxiety and stress

Lion’s Mane mushroom is useful for treating anxiety and depression. This is due to the inflammatory properties of Lion’s Mane. Studies have shown that consuming 0.5 grams of lion’s mane in powder form for four weeks reduces anxiety.

Lion’s Mane helps regenerate brain cells and has a positive effect on the functioning of the hippocampus, the area of the brain that processes emotional responses.

Prevents heart diseases

Studies have shown that Lion’s Mane may reduce the risk of heart disease. Studies conducted on animals have shown that Lion’s Mane prevents the oxidation of cholesterol in the blood. Cholesterol oxidation, which especially increases the risk of arteriosclerosis, heart attack and stroke, can be prevented with Lion’s Mane. Lion’s Mane also reduces the rate of blood clotting.

Risks and side effects of Lion’s Mane

Lion’s Mane can be easily tolerated by the body. However, not using the right amount of Lion’s Mane may cause some side effects.

Side effects of Lion’s Mane:

  • Nausea
  • Skin rash
  • Diarrhea
  • Tingling sensation on the skin
  • Mild nausea
  • Abdominal discomfort

What are the alternatives for hair loss treatment?

Hair loss treatments are determined depending on the cause of hair loss. If you are experiencing male pattern hair loss, it is usually due to high levels of the DHT hormone. But there may be other reasons as well.

The use of medication is the most popular option in the treatment of hair loss. Minoxidil and Finasteride are the most commonly used drugs in hair loss treatments. Hair loss medications can be applied both orally and topically.

If you are experiencing hair loss, you may need to make an appointment with a specialist dermatologist. After the examination by your dermatologist, the cause of your hair loss will be understood. Your dermatologist will give you the right treatment to stop your hair loss and promote hair growth.

Ismail YusibovIsmail Yusibov is the founder and content writer of the AlopeciaTips.

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